Poster Session 7: Stone disease| Volume 8, ISSUE 8, P645, September 2009

S114 Frequency of urolithiasis in primary gout

      Introduction and Objectives

      The prevalence of urolithiasis in primary gout patients has been increased for the past few decades. In earlier studies frequency of primary gout urolothiasis was 20% and now we have data that 37 to 50% patients with gout develop uric acid-related stones. The objective of this study was to assess the frequency and risk factors for urolithiasis in primary gout.

      Material and Methods

      Fifty-five patients with diagnosed primary gout were studied. Urolithiasis was defined as previous history of urolithiasis in clinical records of observed patients or as ultasonografic findings of nephrolithiasis. Next steep was to compare chosen risk factors: patient age, duration of gout, high blood pressure, diabetes and hyperlipidemia between patients with and without urolithiasis.


      In observed group we have 50 (90.90%) males, average age of 56.55 (min 22.00. max 83.00, SD 13.06.). Duration of gout was 6.23 years in average (min 1.00, max 35.00). We found 23 patients (41.8%) with urolithiasis. Ten of them (18.18%) was diagnosed by clinical history and additional 13 (23. 63%) by ultrasonography. In our group 35 (63.6%) patient had hiyperlipidemia, 26 (47. 3%) were with regularly cured high blood pressure, and 14 (25.5%) were diabetics. After statistic evaluation we did not find statistically significant correlation of presents of urolithiasis in gout patients, and their age, hyperlipidemia, high blood pressure and diabetes but we find statically significant correlation between urolothiasis and duration of gout (p < 0.001).


      Frequency of urolithiasis in primary gout in our sample was 41.8%, and 23.63% werw patients with silenmt kidny stone diagnosed by iltrsound. Ultrasonography increased the probability of diagnosing urolithiasis and the most important risc factor is duration of gout.