Introduction and Objectives
We reviewed our 2-yr experience with 18 patients treated for Fournier's Gangrene (FG) to identify the prognostic factors and evaluate this factors for predicting the disease severity and patient survival.
Material and Methods
The medical records of 18 patients with FG who were treated and followed up in our clinic were reviewed. Data were collected in terms of medical history, symptoms, and physical examination findings. Biochemical, hematologic, and bacteriologic study results at admission and at the final evaluation, physical examination findings, The extent of the body surface area (TBSA%), the timing and extent of surgical debridement, and antibiotic therapy were recorded. Fournier's Gangrene Severity Index (FGSI) were evaluated according to whether the patient suvivors or nonsurvivors.
The results were evaluated in two groups: those who survivors (n:14) and nonsurvivors (n:4). Significant differences were found between two groups regarding hemoglobine, hemotocrite, magnesium, alkaline phosphatase levels, body temperature, heart rate and respiration rate, median TBSA%. No significant differences were found between survivors and nonsurvivors regarding other parameters. FGSI score for survivors was 5.00 ± 2.91 (0–10) compared with 13.5 ± 2.62 (9–15) (p:0.001) for nonsurvivors.
Hemotocrite, hemoglobin, creatinine, ALP, TBSA%, FGSI, heart and respiratory rate, rectal involvement and diverting colostomy were determined as an impressive prognostic factors and related to mortality. We defined low magnesium levels as new parameter for poor prognosis. However, we did not find predisposing factors and comorbid conditions to be significantly associated with mortality.
© 2009 European Association of Urology. Published by Elsevier Inc. All rights reserved.