Introduction and Objectives
The effect of peroperative paracetamol infusion on pain in patients with varicocele.
Material and Methods
Fifty-nine patients were randomized in to two groups and microscopic varicocelectomy under local anesthesia with a subinguinal approach were performed. Locally prilocain hydrochloric injection and placebo infusion (isotonic NaCL) was used for the first group. In addition to prilocain hydrochloric, peroperative intravenous paracetamol infusion (20 minutes) was done for the second group. 28 patients were in the first group and 31 patients were in the second. All patients had left varicocele, one was recurrent. Intraoperative and postoperative (half an hour and 4 hours later) pain was assessed by Visual analogue score (VAS).
Mean age for two groups were 21.1 and 21.7 (p > 0.05); mean vein diameters were 3.1 and 3.0 (p > 0.05). Mean VAS were 5.35, 2.8 and 0.67 for group 1; 2.68, 1.51 and 0.51 for group 2. There was statistical significance between peroperative and early postoperative scores for two groups. Although late VAS for group 1 was higher; there was not any statistical significance (p > 0.05). However group 1 had higher postoperative analgesic requirement (25.8% for group 1 and 8.6% for group 2). Side affects were not seen due to infusion and paracetamol.
Peroperative intravenous paracetamol infusion reduces peroperative and postoperative pain and increases the comfort of patients.
© 2009 European Association of Urology. Published by Elsevier Inc. All rights reserved.