Introduction and Objectives
In chronic exacerbated prostatitis, particularly patientes with acut and sever pain, the adminstration of injectable intraproststic antibiotic is one of the managed ways. An equally drug distribution within the whole prostate especially central zone is a therapeutic succusful condition to obtain durable effects. The aim of this study is the evaluation of 3D USG usefullness in controling uniformly located antibiotic within the prostate cells.
Material and Methods
Since the period of 01.01.2006 to 30.06.2009. Intraprostatic antibiotic injection was adminstred in 15 patients. Indication for such a treatment was persistent pain unrelieved after orally drugs adminstration during chronic exacerbated prostatitis. 17 injections performed – one single injection in 14 patientes and 3 injections in one patient in 2 and 3 monthes interval. Age ranged from 26 to 65 years. Average 50.2. Gentamicin (9 times), tazocin (4 times), augmentin (twice), ciprofloxacin (twice) were adminestred intraproststic according to bacteriogram results obtained from seminal cultures. All these injections were performed under transrectal ultrasound control (TRUS). Prostate images acquisition in cross-section (transversal) were achieved after classic TRUS execution. Prostate configuration place and localization has been analized and scheduled for injection after 3D USG performance. USG transducer was used to obsereve prostate in transversal and vertical cross-section. Injectable drugs were given to each lobe in a precise regular and symetrical manner. 3D USG images were achieved after each injection with attention paid to drug distribution at both lobes.
3D USG obtainment allows an accurate evaluation for injectable drugs localization and distribution in the prostate gland. The succsses of such proposal way of treatment was due to the effect of equally drug disposition. Pain complains had relieved after single injection in 14 out of 15 patients. One patient needed 3 injections to gain well therapeutic effect.
3D USG could be a valuable supplement for classic USG examination to precisely evaluate drug distribution and localization after intraprostatic injection. Besides, it could be a method that permits much more an exact drug disposition which in turn raises therapeutic succsses.
© 2009 European Association of Urology. Published by Elsevier Inc. All rights reserved.