Introduction and Objectives
Lymphoma of the bladder is rare tumor. In the literature is described less than 100 cases. Lymphoma representing 0.2% of the primary neoplastic lesions, and 1.8% of secondary lesions in this organ. In some cases about 40% there was a history of chronic cystitis before lymphoma. Lymphoma of the bladder is more common among female than male, the ratio is 6.5:1. The median age of this lesion is about 64 years.The most common cases found in the literature have a low-grade lymphoma inclding the MALT, among cases with high-grade bladder lymphomas the most common is diffuse large cell lymphoma. There is no mortality case of primary lyphoma of the bladder in the literature. In case of non-localised lymphoma an average time of life is 9 years, and in case of secondary lesion 7 months.
Material and Methods
33 years old woman was admitted to Urological Ward because of the tumor of the bladder, which was identified in ultrasonography. This lesion was found accidentally. The patient did not reporte any symptoms. She was classify to transurethral electroresection. In the cystoscopic examination there was found two lesions one on the right wall of the bladder about 2 cm, and the second flat one about 2cm on the left wall. The TUR-B was performed, a sample of the lesions was taken to histopatological examination.
The final result of histopatological examination was: Lymphoma malignum – WHO large B cell lymphoma. The patient was send to Haematology Ward for further examination and treatment – chemotherapy, after one year obtain complete remision of lymphoma – PET-CT examination.
The basis of diagnose is histopatological examination with immunohistochemistry. In the ultrasonography this type of lesion – lymphoma is not to distinguish from a common lesion of the bladder. Chemotherapy with possible additional radiotherapy is the basic treatment of lymphoma in this case.
© 2009 European Association of Urology. Published by Elsevier Inc. All rights reserved.