Poster Session 3: Bladder Cancer| Volume 8, ISSUE 8, P581-582, September 2009

N40 Optical coherent tomography for surgery and urology using: A systematic review

      Introduction and Objectives

      The Optical Coherent Tomography (abbreviated OCT) became a standard diagnostic modality for retinal pathologies nowadays. However, the OCT is exploring for an experimental investigation in surgical branches, especially in urology and basing of this, it is need to clarify any OCT potentials of use. Aim of the study was presenting OCT potentials for imaging in surgery and urology according to literature recourses.

      Material and Methods

      Medial and Scientific bases were searched using “Biopsy in vivo, OCT, Surgery, Urology” as key words. We used MedLine with PubMed tool. 123 items were retrieved. For analysis we used 21 manuscripts (1 report, 7 abstracts, 12 articles and 1 book).


      The principle of OCT consists in lighting by optical radiation of anatomical object under consideration with subsequent light reflection level identifying. It is estimated the spatial resolution of the OCT and the penetration depth as 1–15 μm and up to 4mm appropriately. The OCT as clinical imaging tool has the sensitivity from 60% to 100%, the specificity from 78% to 100%, the positive prognostic validity from 23% to 98% and the negative prognostic validity from 87% to 100%. The OCT was utilized in surgery (colonoscopy, colposcopy etc.) and in urology (cystoscopy).


      OCT could define anatomical structure at the histological layers (epithelium, submucosa and muscle), also intra-operationally it detected topographic features notably neurovascular bundle during prostate visualization. The future works should be for OCT studying with standardization of findings in surgery and urology.