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N33 The rate of incidental prostate cancer in patients who underwent radical cystoprostatectomy and its clinical significance

      Introduction and Objectives

      In this study, we aimed to determine the rate of incidental adenocarcinoma of prostate in patients undergoing radical cystoprostatectomy (RSP) and to assess its clinical importance in the light of literature.

      Material and Methods

      In our clinic from 1995 to 2008 the medical records of 135 (40–82 years) patients with invasive bladder cancer who underwent RSP, were reviewed retrospectively. None of these patients had had any evidence of prostatic adenocarcinoma before cystoprostatectomy. Pathologically, 4 cross sections were routinely taken from each prostate specimens, including one from the apical surgical border.

      Results

      A total of 10 (7.4%) coincidental adenocarcinoma of prostate were detected in 135 patients. Mean age of the patients with prostate carcinoma was 70.2 years (Range:63–80 years). All patients had had normal prostate specific antigen (PSA) levels (1.3–3.4 ng/ml) and normal digital rectal examination findings before surgery. Gleason scores were 4, 5 and 6 in 7, 2 and 1 patient, respectively. All patients with prostate carcinoma had negative surgical border on prostatic apex. All patients had PSA levels less than 0.1 ng/ml on the third month after RSP. Followups of four patients ranged between 52–61 months and no PSA recurrens was recorded.

      Conclusions

      The coincidental presence of prostate cancer with bladder cancer should be kept in mind and therefore detailed pathological examinations should be carried out.