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N31 Detection rate of prostate cancer in double sextant biopsy regions

      Introduction and Objectives

      Our aim was to evaluate the detection rate of prostate cancer in each of the 12-core, or double sextant biopsy region (Naughton et al, 2000), in men undergoing transrectal ultrasound (TRUS)-guided biopsies.

      Material and Methods

      For this purpose 65 men with prostate specific antigen level <15 ng/ml and non-remarkable digital rectal examination underwent transrectal ultrasonographyguided 12-core prostate biopsy due to clinical suspicions of neoplasia. Biopsy was performed by Bard® Magnum® Biopsy Instrument with Quick-Core® Biopsy Needles QC-180020–20T and end fire TRUS-probe. Tumour affected one lobe of prostate in all of these patients according to biopsy result. We evaluated detection rate of prostate cancer in each of double sextant biopsy region.

      Results

      The percent of positive cores on the left and on the right side of prostate was similar (45% vs. 55%). Differences were regarded as statistically insignificant (P > 0.05). Then we measured detection rate in each of the double sextant biopsy region from left and right lobe. The results were the following: laterally directed cores from the apex – 29%, standard cores from the apex – 36%; laterally directed cores from the midgland – 33%, standard cores from the midgland – 43%; laterally directed cores from the base – 33%, standard cores from the base – 35%.

      Conclusions

      The detection rate of prostate cancer in each of double sextant biopsy region was very similar and there are no statistical significant differences between them (P = 0.87–0.23).