Introduction and Objectives
Carcinoma of the prostate is one of the most common male neoplasms. We have been observing tendency to increase both number of CaP cases and deaths caused by this cancer. Strong corelation between age (over fifty) and number of positive diagnosis can be observed. In 2004 prostate cancer took 2nd place in incidentality and 3rd in mortality among all malignant neoplsms. In 2020 20% of polish population will be over 65 years old thats why problem of treating prostate diseases is important and actual.
Aim of the study
The aim of this study is to answer the question: How to improve the reconstruction of prostate MRI imaging to transrectal ultrasound imaging?
Material and Methods
34 males suspicious of prostate cancer and negative result of sextant core biopsy were qualified to this study.All of them undergone with positive result transrectal MRI-Sp examinaton. All of them had transrectal core biopsy targeted on atypical suspicious findings in MRI-Sp. Transrectal biopsy was performed using ultrasonography B-K Medical-2101 Falcon and core biopsy automat Pro-Mag 2.2L Biopsy System Urotech. Biopsies were performed in patients randomly divided into two groups. Group I in which MRI-Sp positive places were localized by use of our own electronical method of MRI images reconstruction and then tranfering them to TRUS image. Group II in which MRI-Sp positive places were localized by use of MRI image only.
Results
Biopsies were performed in patients randomly divided into two groups I-with reconstruction images from MRI-Sp and II without this reconstruction.
Tabled
1
| Result of histopathological examination | Group II, N = 17 (without image reconstruction) N | Group I, N = 17 (with image reconstruction) | ||
|---|---|---|---|---|
| N | % | N | % | |
| Prostate cancer | 4 | 23.5 | 8 | 47.0 |
| PIN II | 1 | 5.8 | 2 | 11.7 |
| Inflammatory changes | 3 | 17.6 | 5 | 29.4 |
| No changes | 9 | 52.9 | 2 | 11.7 |
Conclusions
Proton Magnetic Resonance Spectroscopy Imaging when compared to morphological MR provide additional informations about metabolic changes in prostate tissue. Our own method of localizing and transfering Proton Magnetic Resonance Spectroscopy Images to ultrasonography image increase prostate cancer detectability.
Article info
Identification
Copyright
© 2009 European Association of Urology. Published by Elsevier Inc. All rights reserved.
